Effects of a Peripherally Restricted Hybrid Inhibitor of CB1 Receptors and iNOS on Alcohol Drinking Behavior and Alcohol-Induced Endotoxemia

Effects of a Peripherally Restricted Hybrid Inhibitor of CB1 Receptors and iNOS on Alcohol Drinking Behavior and Alcohol-Induced Endotoxemia

Alcohol consumption is associated with gut dysbiosis, increased intestinal permeability, endotoxemia, and a cascade that leads to persistent systemic inflammation, alcoholic liver disease, and other ailments. Craving for alcohol and its consequences depends, among other things, on the endocannabinoi...

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Detalhes bibliográficos
Main Authors:	Luis Santos-Molina, Alexa Herrerias, Charles N. Zawatsky, Ozge Gunduz-Cinar, Resat Cinar, Malliga R. Iyer, Casey M. Wood, Yuhong Lin, Bin Gao, George Kunos, Grzegorz Godlewski
Formato:	Artigo
Idioma:	English
Publicado em:	MDPI AG 2021-08-01
Colecção:	Molecules
Assuntos:	cannabinoid MRI-1867 hybrid ligand CB1 receptor antagonist iNOS inhibitor rimonabant
Acesso em linha:	https://www.mdpi.com/1420-3049/26/16/5089

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