Photoswitchable Azo- and Diazocine-Functionalized Derivatives of the VEGFR-2 Inhibitor Axitinib
In this study, we aimed at the application of the concept of photopharmacology to the approved vascular endothelial growth factor receptor (VEGFR)-2 kinase inhibitor axitinib. In a previous study, we found out that the photoisomerization of axitinib’s stilbene-like double bond is unidirectional in a...
Main Authors: | Linda Heintze, Dorian Schmidt, Theo Rodat, Lydia Witt, Julia Ewert, Malte Kriegs, Rainer Herges, Christian Peifer |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-11-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/23/8961 |
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