Non-canonical function of an Hif-1α splice variant contributes to the sustained flight of locusts

Non-canonical function of an Hif-1α splice variant contributes to the sustained flight of locusts

The hypoxia inducible factor (Hif) pathway is functionally conserved across metazoans in modulating cellular adaptations to hypoxia. However, the functions of this pathway under aerobic physiological conditions are rarely investigated. Here, we show that Hif-1α2, a locust Hif-1α isoform, does not in...

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Bibliographic Details
Main Authors: Ding Ding, Jie Zhang, Baozhen Du, Xuanzhao Wang, Li Hou, Siyuan Guo, Bing Chen, Le Kang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-08-01
Series:eLife
Subjects:
animal flight
hypoxia inducible factor
energy metabolism
Dj-1
alternative splicing
redox homeostasis
Online Access:https://elifesciences.org/articles/74554

Internet

https://elifesciences.org/articles/74554

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