Functional Analysis of Rhomboid Proteases during <italic toggle="yes">Toxoplasma</italic> Invasion

ABSTRACT Host cell invasion by Toxoplasma gondii and other apicomplexan parasites requires transmembrane adhesins that mediate binding to receptors on the substrate and host cell to facilitate motility and invasion. Rhomboid proteases (ROMs) are thought to cleave adhesins within their transmembrane...

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Bibliographic Details
Main Authors: Bang Shen, Jeffrey S. Buguliskis, Tobie D. Lee, L. David Sibley
Format: Article
Language:English
Published: American Society for Microbiology 2014-10-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.01795-14