Basal late sodium current is a significant contributor to the duration of action potential of guinea pig ventricular myocytes

Abstract In cardiac myocytes, an enhancement of late sodium current (INaL) under pathological conditions is known to cause prolongation of action potential duration (APD). This study investigated the contribution of INaL under basal, physiological conditions to the APD. Whole‐cell INaL and the APD o...

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Bibliographic Details
Main Authors: Yejia Song, Luiz Belardinelli
Format: Article
Language:English
Published: Wiley 2017-05-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.13295