Cyclooxygenase-2 in adipose tissue macrophages limits adipose tissue dysfunction in obese mice

Cyclooxygenase-2 in adipose tissue macrophages limits adipose tissue dysfunction in obese mice

Obesity-associated complications are causing increasing morbidity and mortality worldwide. Expansion of adipose tissue in obesity leads to a state of low-grade chronic inflammation and dysregulated metabolism, resulting in insulin resistance and metabolic syndrome. Adipose tissue macrophages (ATMs)...

Full description

Bibliographic Details
Main Authors: Yu Pan, Shirong Cao, Jiaqi Tang, Juan P. Arroyo, Andrew S. Terker, Yinqiu Wang, Aolei Niu, Xiaofeng Fan, Suwan Wang, Yahua Zhang, Ming Jiang, David H. Wasserman, Ming-Zhi Zhang, Raymond C. Harris
Format: Article
Language:English
Published: American Society for Clinical Investigation 2022-05-01
Series:The Journal of Clinical Investigation
Subjects:
Inflammation
Metabolism
Online Access:https://doi.org/10.1172/JCI152391

Internet

https://doi.org/10.1172/JCI152391

Similar Items