A Case of Daratumumab-Induced Significant Decrease in Donor-Specific HLA Antibodies and Remission Induction Before Haploidentical Stem Cell Transplantation in a Refractory B-ALL Patient

Objective: To explore the method of eliminating donor-specific anti-HLA antibodies (DSA) in haploidentical stem cell transplantation (haplo-SCT). Methods: We present a refractory B-cell acute lymphoblastic leukemia (ALL) patient who had strongly positive DSA, but had no human leukocyte antigen–match...

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Bibliographic Details
Main Authors: Xin Li, Haibo Zhu, Tao Sui, Xingli Zhao, Qi Deng
Format: Article
Language:English
Published: SAGE Publishing 2022-10-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/09636897221132502