Comparison of Magnetic Resonance Imaging and Serum Biomarkers for Detection of Human Pluripotent Stem Cell-Derived Teratomas

Comparison of Magnetic Resonance Imaging and Serum Biomarkers for Detection of Human Pluripotent Stem Cell-Derived Teratomas

The use of cells derived from pluripotent stem cells (PSCs) for regenerative therapies confers a considerable risk for neoplastic growth and teratoma formation. Preclinical and clinical assessment of such therapies will require suitable monitoring strategies to understand and mitigate these risks. H...

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Bibliographic Details
Main Authors: Johannes Riegler, Antje Ebert, Xulei Qin, Qi Shen, Mouer Wang, Mohamed Ameen, Kazuki Kodo, Sang-Ging Ong, Won Hee Lee, Grace Lee, Evgenios Neofytou, Joseph D. Gold, Andrew J. Connolly, Joseph C. Wu
Format: Article
Language:English
Published: Elsevier 2016-02-01
Series:Stem Cell Reports
Subjects:
magnetic resonance imaging
ultrasound imaging
serum biomarker
microRNA biomarker
pluripotent stem cells
tumorigenicity
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671115003732

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http://www.sciencedirect.com/science/article/pii/S2213671115003732

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