Association between oral and fecal microbiome dysbiosis and treatment complications in pediatric patients undergoing allogeneic hematopoietic stem cell transplantation

Association between oral and fecal microbiome dysbiosis and treatment complications in pediatric patients undergoing allogeneic hematopoietic stem cell transplantation

Abstract The oral and gastrointestinal mucosae represent the main targets of the toxic effect of chemo and/or radiotherapy administered during the conditioning regimen before hematopoietic stem cell transplant (HSCT). These harmful consequences and the immunological complications that may occur afte...

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Bibliographic Details
Main Authors: M. Faraci, C. Bonaretti, G. Dell’Orso, F. Pierri, S. Giardino, F. Angiero, S. Blasi, G. Farronato, E. Di Marco, A. Trevisiol, E. Olcese, L. Rufino, M. Squillario, R. Biassoni
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
Oral microbiome
Gut microbiome
Hematopoietic stem cell transplant (HSCT)
Mucositis
Graft versus host disease (GvHD)
Online Access:https://doi.org/10.1038/s41598-024-55690-6

Internet

https://doi.org/10.1038/s41598-024-55690-6

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