Type I Interferon (IFN)-Regulated Activation of Canonical and Non-Canonical Signaling Pathways

For several decades there has been accumulating evidence implicating type I interferons (IFNs) as key elements of the immune response. Therapeutic approaches incorporating different recombinant type I IFN proteins have been successfully employed to treat a diverse group of diseases with significant...

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Bibliographic Details
Main Authors: Candice Mazewski, Ricardo E. Perez, Eleanor N. Fish, Leonidas C. Platanias
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.606456/full