Synechococcus elongatus Argonaute reduces natural transformation efficiency and provides immunity against exogenous plasmids

Synechococcus elongatus Argonaute reduces natural transformation efficiency and provides immunity against exogenous plasmids

ABSTRACT The cyanobacterium Synechococcus elongatus PCC 7942 produces an active prokaryotic Argonaute nuclease, SeAgo, whose function is unknown. Here, we show that SeAgo reduces natural transformation and prevents the maintenance of RSF1010 replicons in S. elongatus. In addition, a Cas4-like nuclea...

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Bibliographic Details
Main Authors: Arnaud Taton, Tami S. Gilderman, Dustin C. Ernst, Carla A. Omaga, Lucas A. Cohen, Camilo Rey-Bedon, James W. Golden, Susan S. Golden
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:mBio
Subjects:
cyanobacteria
horizontal gene transfer
Argonaute
cyanophage
plasmid
genetic engineering
Online Access:https://journals.asm.org/doi/10.1128/mbio.01843-23

Internet

https://journals.asm.org/doi/10.1128/mbio.01843-23

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