Flagellin is essential for initial attachment to mucosal surfaces by Clostridioides difficile

Flagellin is essential for initial attachment to mucosal surfaces by Clostridioides difficile

ABSTRACT Mucins are glycoproteins which can be found in host cell membranes and as a gelatinous surface formed from secreted mucins. Mucosal surfaces in mammals form a barrier to invasive microbes, particularly bacteria, but are a point of attachment for others. Clostridioides difficile is an anaero...

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Bibliographic Details
Main Authors: Ben Sidner, Armando Lerma, Baishakhi Biswas, Thi Van Thanh Do, Yafan Yu, Leslie A. Ronish, Hugh McCullough, Jennifer M. Auchtung, Kurt H. Piepenbrink
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:Microbiology Spectrum
Subjects:
C. difficile
host-pathogen interactions
flagella
protein-glycan interactions
glycoproteins
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02120-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.02120-23

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