CircHIPK3 negatively regulates autophagy by blocking VCP binding to the Beclin 1 complex in bladder cancer

CircHIPK3 negatively regulates autophagy by blocking VCP binding to the Beclin 1 complex in bladder cancer

Abstract Circular RNA HIPK3 (circHIPK3) mediates the progression of multiple cancers, including bladder cancer, by regulating cell migration, autophagy and epithelial mesenchymal transition. However, the mechanism by which circHIPK3 regulates autophagy in bladder cancer cells remains unclear. Autoph...

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Bibliographic Details
Main Authors: Chong Wang, Tiantian Liu, Jiawei Wang, Chao Cheng, Ze Zhang, Jingwei Zhang, Houbao Huang, Yawei Li
Format: Article
Language:English
Published: Springer 2023-06-01
Series:Discover Oncology
Subjects:
Circular RNA
RNA-binding proteins (RBPs)
Autophagy
VCP
Bladder cancer
Online Access:https://doi.org/10.1007/s12672-023-00689-0

Internet

https://doi.org/10.1007/s12672-023-00689-0

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