Zoledronic acid treatment impairs protein geranyl-geranylation for biological effects in prostatic cells

<p>Abstract</p> <p>Background</p> <p>Nitrogen-containing bisphosphonates (N-BPs) have been designed to inhibit osteoclast-mediated bone resorption. However, it is now accepted that part of their anti-tumor activities is related to interference with the mevalonate pathwa...

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Bibliographic Details
Main Authors: Weinbaum Carolyn, Faye JC, Lajoie-Mazenc I, Pradines A, Thoulouzan M, Goffinet M, Séronie-Vivien S
Format: Article
Language:English
Published: BMC 2006-03-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/6/60