Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability

Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability

Endothelial to mesenchymal transition (EndMT) is a crucial developmental process that also plays a role in the pathogenesis of some diseases. Here the authors show that EndMT contributes to the development of atherosclerosis in mice and humans, and is associated with complex human plaques that may b...

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Bibliographic Details
Main Authors: Solene M. Evrard, Laura Lecce, Katherine C. Michelis, Aya Nomura-Kitabayashi, Gaurav Pandey, K-Raman Purushothaman, Valentina d’Escamard, Jennifer R. Li, Lahouaria Hadri, Kenji Fujitani, Pedro R. Moreno, Ludovic Benard, Pauline Rimmele, Ariella Cohain, Brigham Mecham, Gwendalyn J. Randolph, Elizabeth G. Nabel, Roger Hajjar, Valentin Fuster, Manfred Boehm, Jason C. Kovacic
Format: Article
Language:English
Published: Nature Portfolio 2016-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11853

Internet

https://doi.org/10.1038/ncomms11853

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