Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability
Endothelial to mesenchymal transition (EndMT) is a crucial developmental process that also plays a role in the pathogenesis of some diseases. Here the authors show that EndMT contributes to the development of atherosclerosis in mice and humans, and is associated with complex human plaques that may b...
Main Authors: | Solene M. Evrard, Laura Lecce, Katherine C. Michelis, Aya Nomura-Kitabayashi, Gaurav Pandey, K-Raman Purushothaman, Valentina d’Escamard, Jennifer R. Li, Lahouaria Hadri, Kenji Fujitani, Pedro R. Moreno, Ludovic Benard, Pauline Rimmele, Ariella Cohain, Brigham Mecham, Gwendalyn J. Randolph, Elizabeth G. Nabel, Roger Hajjar, Valentin Fuster, Manfred Boehm, Jason C. Kovacic |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2016-06-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms11853 |
Similar Items
-
Correction: Corrigendum: Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability
by: Solene M. Evrard, et al.
Published: (2017-02-01) -
CD90 Identifies Adventitial Mesenchymal Progenitor Cells in Adult Human Medium- and Large-Sized Arteries
by: Katherine C. Michelis, et al.
Published: (2018-07-01) -
New vessel formation in the context of cardiomyocyte regeneration – the role and importance of an adequate perfusing vasculature
by: Katherine C. Michelis, et al.
Published: (2014-11-01) -
Molecular and Genetic Profiling for Precision Medicines in Pulmonary Arterial Hypertension
by: Shahood Fazal, et al.
Published: (2021-03-01) -
CXCR4 and CXCR7 play distinct roles in cardiac lineage specification and pharmacologic β-adrenergic response
by: Delaine K. Ceholski, et al.
Published: (2017-08-01)