Mechanism of Action of Ketogenic Diet Treatment: Impact of Decanoic Acid and Beta—Hydroxybutyrate on Sirtuins and Energy Metabolism in Hippocampal Murine Neurons

The ketogenic diet (KD), a high-lipid and low-carbohydrate diet, has been used in the treatment of epilepsy, neurodegenerative disorders, inborn errors of metabolism and cancer; however, the exact mechanism/s of its therapeutic effect is not completely known. We hypothesized that sirtuins (SIRT)—a g...

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Bibliographic Details
Main Authors: Partha Dabke, Anibh M. Das
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/12/8/2379