Detecting recurrent passenger mutations in melanoma by targeted UV damage sequencing

Abstract Sequencing of melanomas has identified hundreds of recurrent mutations in both coding and non-coding DNA. These include a number of well-characterized oncogenic driver mutations, such as coding mutations in the BRAF and NRAS oncogenes, and non-coding mutations in the promoter of telomerase...

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Bibliographic Details
Main Authors: Kathiresan Selvam, Smitha Sivapragasam, Gregory M. K. Poon, John J. Wyrick
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-38265-3