Regulation of axonal HCN1 trafficking in perforant path involves expression of specific TRIP8b isoforms.

The functions of HCN channels in neurons depend critically on their subcellular localization, requiring fine-tuned machinery that regulates subcellular channel trafficking. Here we provide evidence that regulatory mechanisms governing axonal HCN channel trafficking involve association of the channel...

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Bibliographic Details
Main Authors: Wiebke Wilkars, Zhiqiang Liu, Alan S Lewis, Travis R Stoub, Elena M Ramos, Nicola Brandt, Daniel A Nicholson, Dane M Chetkovich, Roland A Bender
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3283722?pdf=render