Downregulated lncRNA HOXA11-AS Affects Trophoblast Cell Proliferation and Migration by Regulating RND3 and HOXA7 Expression in PE

The long noncoding RNA HOXA11-AS displays abnormal expression in numerous human diseases. However, its function and biological mechanisms remain unclear in preeclampsia (PE). In this study, we report that HOXA11-AS is significantly downregulated in preeclamptic placental tissues and could contribute...

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Bibliographic Details
Main Authors: Yetao Xu, Dan Wu, Jie Liu, Shiyun Huang, Qing Zuo, Xi Xia, Ying Jiang, Sailan Wang, Yanzi Chen, Tianjun Wang, Lizhou Sun
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Molecular Therapy: Nucleic Acids
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253118301045