Machine Learning-Enhanced T Cell Neoepitope Discovery for Immunotherapy Design
Immune responses mediated by T cells are aimed at specific peptides, designated T cell epitopes, that are recognized when bound to human leukocyte antigen (HLA) molecules. The HLA genes are remarkably polymorphic in the human population allowing a broad and fine-tuned capacity to bind a wide array o...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2019-05-01
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| Series: | Cancer Informatics |
| Online Access: | https://doi.org/10.1177/1176935119852081 |