Lymphatic Metastasis of NSCLC Involves Chemotaxis Effects of Lymphatic Endothelial Cells through the CCR7–CCL21 Axis Modulated by TNF-α

Metastasis and recurrence are the main causes of lung adenocarcinoma patients’ death. Lymphatic metastasis is the main way of non-small cell lung cancer (NSCLC) metastasis. C-C chemokine receptor type 7 (CCR7) overexpression has been demonstrated to mediate occurrence and progression of NSCLC. Moreo...

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Bibliographic Details
Main Authors: Shuai Zhang, Hongzheng Wang, Zhiyun Xu, Yongkang Bai, Lin Xu
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/11/11/1309