Multifaceted entrancing role of glucose and its analogue, 2-deoxy-D-glucose in cancer cell proliferation, inflammation, and virus infection

Multifaceted entrancing role of glucose and its analogue, 2-deoxy-D-glucose in cancer cell proliferation, inflammation, and virus infection

Chronic exposure to high glucose inside the human body helps in the progression of cancer by activating various signaling pathways including PI3K, Akt, mTOR, Ras, Raf, MAPK, and PKC. Hyperglycemia induces ROS and AGE production and decreases the functional activities of the cellular antioxidant syst...

Full description

Bibliographic Details
Main Authors: Sananda Dey, Nensina Murmu, Tanushree Mondal, Ishita Saha, Soumendranath Chatterjee, Rahul Manna, Subhash Haldar, Sandeep K. Dash, Tapasree Roy Sarkar, Biplab Giri
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Glucose
2-deoxy-D-glucose
Cancer
Cell proliferation
Inflammation
Viral infection
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222011908

Internet

http://www.sciencedirect.com/science/article/pii/S0753332222011908

Similar Items