Estradiol Binds to Insulin and Insulin Receptor Decreasing Insulin Binding in vitro

Rationale: Insulin resistance associated with hyperestrogenemias occurs in gestational diabetes mellitus, polycystic ovary syndrome, ovarian hyperstimulation syndrome, estrogen therapies, metabolic syndrome and obesity. The mechanism by which insulin and estrogen interact is unknown. We hypothesize...

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Bibliographic Details
Main Authors: Robert eRoot-Bernstein, Patrick F. Dillon, Abigail ePodufaly
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2014.00118/full