Inhibition of neuronal apoptosis and axonal regression ameliorates sympathetic atrophy and hemodynamic alterations in portal hypertensive rats.

Inhibition of neuronal apoptosis and axonal regression ameliorates sympathetic atrophy and hemodynamic alterations in portal hypertensive rats.

BACKGROUND AND AIM:A neuronal pathway participates in the development of portal hypertension: blockade of afferent sensory nerves in portal vein ligated (PVL) rats simultaneously prevents brain cardiovascular regularory nuclei activation, neuromodulator overexpression in superior mesenteric ganglia,...

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Bibliographic Details
Main Authors: Nahia Ezkurdia, Imma Raurell, Sarai Rodríguez, Antonio González, Rafael Esteban, Joan Genescà, María Martell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3882227?pdf=render

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http://europepmc.org/articles/PMC3882227?pdf=render

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