Selecting for CRISPR-Edited Knock-In Cells
CRISPR technology affords a simple and robust way to edit the genomes of cells, providing powerful tools for basic research and medicine. While using Cas9 to target a genomic site is very efficient, making a specific mutation at that site is much less so, as it depends on the endogenous DNA repair m...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-10-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/23/19/11919 |