Biotransformation of Phytosterols to Androst-1,4-Diene-3,17-Dione by <i>Mycobacterium</i> sp. ZFZ Expressing 3-Ketosteroid-Δ<sup>1</sup>-Dehydrogenase
As an important hormone drug intermediate, androst-1,4-diene-3,17-dione can be bio-converted from phytosterols. However, separation and purification in the downstream process are very difficult due to the similarity in structure and physiological characteristics between ADD and androstenedione (AD)....
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-06-01
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| Series: | Catalysts |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4344/10/6/663 |