Pharmacological targeting PIKfyve and tubulin as an effective treatment strategy for double-hit lymphoma

Pharmacological targeting PIKfyve and tubulin as an effective treatment strategy for double-hit lymphoma

Abstract Double-hit lymphoma is one of the most aggressive and refractory lymphoma subtypes with recurrent genetic abnormalities of MYC and BCL-2 or BCL6 rearrangement, leading to a poor prognosis in the present clinical practice. Therefore, new therapeutic strategies for eliminating double-hit lymp...

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Bibliographic Details
Main Authors: Liying Feng, Kai Chen, Wei Huang, Yuelong Jiang, Xihuan Sun, Yong Zhou, Li Li, Yin Li, Xianming Deng, Bing Xu
Format: Article
Language:English
Published: Nature Publishing Group 2022-01-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-00833-9

Internet

https://doi.org/10.1038/s41420-022-00833-9

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