Treatment of peritoneal carcinomatosis by targeted delivery of the radio-labeled tumor homing peptide bi-DTPA-[F3]2 into the nucleus of tumor cells.

Treatment of peritoneal carcinomatosis by targeted delivery of the radio-labeled tumor homing peptide bi-DTPA-[F3]2 into the nucleus of tumor cells.

BACKGROUND: Alpha-particle emitting isotopes are effective novel tools in cancer therapy, but targeted delivery into tumors is a prerequisite of their application to avoid toxic side effects. Peritoneal carcinomatosis is a widespread dissemination of tumors throughout the peritoneal cavity. As perit...

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Bibliographic Details
Main Authors: Enken Drecoll, Florian C Gaertner, Matthias Miederer, Birgit Blechert, Mario Vallon, Jan M Müller, Andrea Alke, Christof Seidl, Frank Bruchertseifer, Alfred Morgenstern, Reingard Senekowitsch-Schmidtke, Markus Essler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2682652?pdf=render

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http://europepmc.org/articles/PMC2682652?pdf=render

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