Design, Synthesis, and Evaluation of the COX-2 Inhibitory Activities of New 1,3-Dihydro-<i>2H</i>-indolin-2-one Derivatives
Thirty-three 1,3-dihydro-<i>2H</i>-indolin-2-one derivatives bearing α, β-unsaturated ketones were designed and synthesized via the Knoevenagel condensation reaction. The cytotoxicity, in vitro anti-inflammatory ability, and in vitro COX-2 inhibitory activity of all the compounds were ev...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-06-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/28/12/4668 |