Circulating Mitochondrial-Derived Vesicles, Inflammatory Biomarkers and Amino Acids in Older Adults With Physical Frailty and Sarcopenia: A Preliminary BIOSPHERE Multi-Marker Study Using Sequential and Orthogonalized Covariance Selection – Linear Discriminant Analysis

Circulating Mitochondrial-Derived Vesicles, Inflammatory Biomarkers and Amino Acids in Older Adults With Physical Frailty and Sarcopenia: A Preliminary BIOSPHERE Multi-Marker Study Using Sequential and Orthogonalized Covariance Selection – Linear Discriminant Analysis

Physical frailty and sarcopenia (PF&S) is a prototypical geriatric condition characterized by reduced physical function and low muscle mass. The multifaceted pathophysiology of this condition recapitulates all hallmarks of aging making the identification of specific biomarkers challenging. I...

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Bibliographic Details
Main Authors: Emanuele Marzetti, Flora Guerra, Riccardo Calvani, Federico Marini, Alessandra Biancolillo, Jacopo Gervasoni, Aniello Primiano, Hélio José Coelho-Júnior, Francesco Landi, Roberto Bernabei, Cecilia Bucci, Anna Picca
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
aging
biomarkers
cytokines
extracellular vesicles
geroscience
metabolomics
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.564417/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.564417/full

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