DE-kupl: exhaustive capture of biological variation in RNA-seq data through k-mer decomposition

DE-kupl: exhaustive capture of biological variation in RNA-seq data through k-mer decomposition

Abstract We introduce a k-mer-based computational protocol, DE-kupl, for capturing local RNA variation in a set of RNA-seq libraries, independently of a reference genome or transcriptome. DE-kupl extracts all k-mers with differential abundance directly from the raw data files. This enables the retri...

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Bibliographic Details
Main Authors: Jérôme Audoux, Nicolas Philippe, Rayan Chikhi, Mikaël Salson, Mélina Gallopin, Marc Gabriel, Jérémy Le Coz, Emilie Drouineau, Thérèse Commes, Daniel Gautheret
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Genome Biology
Online Access:http://link.springer.com/article/10.1186/s13059-017-1372-2

Internet

http://link.springer.com/article/10.1186/s13059-017-1372-2

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