Styryl Quinazolinones as Potential Inducers of Myeloid Differentiation via Upregulation of C/EBPα

Styryl Quinazolinones as Potential Inducers of Myeloid Differentiation via Upregulation of C/EBPα

The CCAAT enhancer-binding protein α (C/EBPα) plays an important role in myeloid cell differentiation and in the enhancement of C/EBPα expression/activity, which can lead to granulocytic differentiation in acute myeloid leukemia (AML) cells. We found that styryl quinazo...

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Bibliographic Details
Main Authors: Radhakrishnan Sridhar, Hisashi Takei, Riyaz Syed, Ikei S. Kobayashi, Liu Bee Hui, Ahmed Kamal, Daniel G. Tenen, Susumu S. Kobayashi
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Molecules
Subjects:
myeloid differentiation
CCAAT/enhancer binding protein α
Online Access:http://www.mdpi.com/1420-3049/23/8/1938

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http://www.mdpi.com/1420-3049/23/8/1938

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