Metabolomic profiling of CSF and blood serum elucidates general and sex-specific patterns for mild cognitive impairment and Alzheimer’s disease patients

Metabolomic profiling of CSF and blood serum elucidates general and sex-specific patterns for mild cognitive impairment and Alzheimer’s disease patients

BackgroundBeta-amyloid (Abeta) and tau protein in cerebrospinal fluid (CSF) are established diagnostic biomarkers for Alzheimer’s disease (AD). However, these biomarkers may not the only ones existing parameters that reflect Alzheimer’s disease neuropathological change. The use of quantitative metab...

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Bibliographic Details
Main Authors: Georgy Berezhnoy, Christoph Laske, Christoph Trautwein
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Aging Neuroscience
Subjects:
brain
dementia
cerebrospinal fluid
metabolism
neurodegeneration
memory
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1219718/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2023.1219718/full

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