The cytokine IL-27 reduces inflammation and protects photoreceptors in a mouse model of retinal degeneration

Abstract Background Retinal degenerative diseases are a group of conditions characterized by photoreceptor death and vision loss. Excessive inflammation and microglial activation contribute to the pathology of retinal degenerations and a major focus in the field is identifying more effective anti-in...

Full description

Bibliographic Details
Main Authors: Andrea Nortey, Kimberly Garces, Tal Carmy-Bennun, Abigail S. Hackam
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:https://doi.org/10.1186/s12974-022-02576-x