Deciphering the regulatory genome of Escherichia coli, one hundred promoters at a time

Deciphering the regulatory genome of Escherichia coli, one hundred promoters at a time

Advances in DNA sequencing have revolutionized our ability to read genomes. However, even in the most well-studied of organisms, the bacterium Escherichia coli, for ≈65% of promoters we remain ignorant of their regulation. Until we crack this regulatory Rosetta Stone, efforts to read and write genom...

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Bibliographic Details
Main Authors: William T Ireland, Suzannah M Beeler, Emanuel Flores-Bautista, Nicholas S McCarty, Tom Röschinger, Nathan M Belliveau, Michael J Sweredoski, Annie Moradian, Justin B Kinney, Rob Phillips
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-09-01
Series:eLife
Subjects:
transcriptional regulation
information theory
quantitative biology
gene expression
transcription factors
Online Access:https://elifesciences.org/articles/55308

Internet

https://elifesciences.org/articles/55308

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