A comprehensive framework for trans-ancestry pathway analysis using GWAS summary data from diverse populations.

As more multi-ancestry GWAS summary data become available, we have developed a comprehensive trans-ancestry pathway analysis framework that effectively utilizes this diverse genetic information. Within this framework, we evaluated various strategies for integrating genetic data at different levels-S...

Full description

Bibliographic Details
Main Authors: Sheng Fu, William Wheeler, Xiaoyu Wang, Xing Hua, Devika Godbole, Jubao Duan, Bin Zhu, Lu Deng, Fei Qin, Haoyu Zhang, Jianxin Shi, Kai Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-10-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1011322