Ibuprofen Decreases Cytokine-Induced Amyloid Beta Production in Neuronal Cells

Ibuprofen Decreases Cytokine-Induced Amyloid Beta Production in Neuronal Cells

Trying to decrease the production of Amyloid beta (Aβ) has been envisaged as a promising approach to prevent neurodegeneration in Alzheimer's disease (AD). A chronic inflammatory reaction with activated microglia cells and astrocytes is a constant feature of AD. The participation of the immune...

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Bibliographic Details
Main Authors: Imrich Blasko, Alexandra Apochal, Guenther Boeck, Tobias Hartmann, Beatrix Grubeck-Loebenstein, Gerhard Ransmayr
Format: Article
Language:English
Published: Elsevier 2001-12-01
Series:Neurobiology of Disease
Subjects:
ibuprofen
proinflammatory cytokines
amyloid beta
BACE-1
Alzheimer's disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996101904516

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http://www.sciencedirect.com/science/article/pii/S0969996101904516

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