Dynamic Phosphorylation of G9a Regulates its Repressive Activity on Chromatin Accessibility and Mitotic Progression

Dynamic Phosphorylation of G9a Regulates its Repressive Activity on Chromatin Accessibility and Mitotic Progression

Abstract Phosphorylation of Ser10 of histone H3 (H3S10p), together with the adjacent methylation of Lys9 (H3K9me), has been proposed to function as a ‘phospho‐methyl switch’ to regulate mitotic chromatin architecture. Despite of immense understanding of the roles of H3S10 phosphorylation, how H3K9me...

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Chi tiết về thư mục
Những tác giả chính: Qizhi Geng, Yue‐Yu Kong, Weizhe Li, Jianhao Zhang, Haoli Ma, Yuhang Zhang, Lin‐Tai Da, Yan Zhao, Hai‐Ning Du
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: Wiley 2023-10-01
Loạt:Advanced Science
Những chủ đề:
chromatin accessibility
G9a phosphorylation
mitotic progression
Plk1, PPP2CB
Truy cập trực tuyến:https://doi.org/10.1002/advs.202303224

Internet

https://doi.org/10.1002/advs.202303224

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