Dissecting the process of human neutrophil lineage determination by using alpha-lipoic acid inducing neutrophil deficiency model

Dissecting the process of human neutrophil lineage determination by using alpha-lipoic acid inducing neutrophil deficiency model

Granulocyte-monocyte progenitors (GMPs) differentiate into both neutrophils and monocytes. Recently, uni-potential neutrophil progenitors have been identified both in mice and humans using an array of surface markers. However, how human GMPs commit to neutrophil progenitors and the regulatory mechan...

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Bibliographic Details
Main Authors: Yong Dong, Yimeng Zhang, Yongping Zhang, Xu Pan, Ju Bai, Yijin Chen, Ya Zhou, Zhenyang Lai, Qiang Chen, Shaoyan Hu, Qiongxiu Zhou, Yonggang Zhang, Feng Ma
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Redox Biology
Subjects:
Alpha-lipoic acid
Neutrophils
Monocytes
ELK1
SF3B1
RNA splicing
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722001641

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http://www.sciencedirect.com/science/article/pii/S2213231722001641

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