Acute Graft-Versus-Host Disease After Humanized Anti-CD19-CAR T Therapy in Relapsed B-ALL Patients After Allogeneic Hematopoietic Stem Cell Transplant

Acute Graft-Versus-Host Disease After Humanized Anti-CD19-CAR T Therapy in Relapsed B-ALL Patients After Allogeneic Hematopoietic Stem Cell Transplant

We studied the acute graft-versus-host disease (GVHD) after humanized anti-CD19-CAR T therapy in relapsed B-acute lymphoblastic leukemia (ALL) patients after allogeneic hematopoietic stem cell transplant (allo-HSCT). Fifteen B-ALL patients were enrolled in our study. Thirteen patients (86.67%) achie...

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Bibliographic Details
Main Authors: Pengjiang Liu, Meijing Liu, Cuicui Lyu, Wenyi Lu, Rui Cui, Jia Wang, Qing Li, Nan Mou, Qi Deng, Donglin Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Oncology
Subjects:
acute lymphoblastic leukemia
relapse
allogeneic hematopoietic stem cell transplantation
chimeric antigen receptor (CARs)
graft-versus-host disease
cytokine release syndrome
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.573822/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.573822/full

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