Presenilin1 inhibits glioblastoma cell invasiveness via promoting Sortilin cleavage

Presenilin1 inhibits glioblastoma cell invasiveness via promoting Sortilin cleavage

Abstract Background Alzheimer’s disease (AD) and glioblastoma are the most common and devastating diseases in the neurology and neurosurgery departments, respectively. Our previous research reports that the AD-related protein Presenilin1 represses cell proliferation by inhibiting the Wnt/β-catenin p...

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Bibliographic Details
Main Authors: Wei Yang, Yan Xiang, Mao-Jun Liao, Peng-Fei Wu, Lin Yang, Guo-Hao Huang, Bao-Zhong Shi, Liang Yi, Sheng-Qing Lv
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Cell Communication and Signaling
Subjects:
Presenilin1
Cleavage
Sortilin
Glioblastoma
Invasion
Online Access:https://doi.org/10.1186/s12964-021-00780-5

Internet

https://doi.org/10.1186/s12964-021-00780-5

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