Rosemary Extract-Induced Autophagy and Decrease in Accumulation of Collagen Type I in Osteogenesis Imperfecta Skin Fibroblasts

Rosemary Extract-Induced Autophagy and Decrease in Accumulation of Collagen Type I in Osteogenesis Imperfecta Skin Fibroblasts

Osteogenesis imperfecta (OI) is a heterogeneous connective tissue disease mainly caused by structural mutations in type I collagen. Mutant collagen accumulates intracellularly, causing cellular stress that has recently been shown to be phenotype-related. Therefore, the aim of the study was to search...

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Bibliographic Details
Main Authors: Joanna Sutkowska-Skolimowska, Justyna Brańska-Januszewska, Jakub W. Strawa, Halina Ostrowska, Malwina Botor, Katarzyna Gawron, Anna Galicka
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
rosemary extract
collagen type I
unfolded protein response
autophagy
proteasome
skin fibroblasts
Online Access:https://www.mdpi.com/1422-0067/23/18/10341

Internet

https://www.mdpi.com/1422-0067/23/18/10341

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