Stringent response ensures the timely adaptation of bacterial growth to nutrient downshift

Bacteria undergo nutrient fluctuations during repeated feast and famine cycles and need to metabolically adapt to these changes. Using quantitative proteomics, Zhu & Dai show that the stringent response of (p)ppGpp is crucial for the timely adaption of bacterial growth to both amino acid and car...

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Bibliographic Details
Main Authors: Manlu Zhu, Xiongfeng Dai
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-36254-0