Indoleamine 2,3-Dioxygenase (IDO) Activity: A Perspective Biomarker for Laboratory Determination in Tumor Immunotherapy

Indoleamine 2,3-dioxygenase 1 (IDO1) is a heme enzyme involved in catalyzing the conversion of tryptophan (Trp) into kynurenine (Kyn) at the first rate-limiting step in the kynurenine pathway of L-tryptophan metabolism. It has been found to be involved in several biological functions such as aging,...

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Bibliographic Details
Main Authors: Pengbo Yang, Junhua Zhang
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/11/7/1988