The progress and prospect of homologous recombination deficiency detection in clinical diagnosis and treatment of cancer
Homologous recombination (HR) is the main way to repair DNA double-stranded breaks, single-stranded DNA gaps and stagnation or folding replication forks, helping to maintain telomeres and ensure the correct segregation of chromosomes during meiosis. Homologous recombination repair (HRR) pathway is o...
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Format: | Article |
Language: | English |
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Editorial Office of China Oncology
2021-04-01
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Series: | Zhongguo aizheng zazhi |
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Online Access: | http://www.china-oncology.com/fileup/1007-3639/PDF/20210415.pdf |