The progress and prospect of homologous recombination deficiency detection in clinical diagnosis and treatment of cancer

Homologous recombination (HR) is the main way to repair DNA double-stranded breaks, single-stranded DNA gaps and stagnation or folding replication forks, helping to maintain telomeres and ensure the correct segregation of chromosomes during meiosis. Homologous recombination repair (HRR) pathway is o...

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Bibliographic Details
Main Author: YU Li , SHEN Minna , JIANG Huiqin , WANG Beili , GUO Wei
Format: Article
Language:English
Published: Editorial Office of China Oncology 2021-04-01
Series:Zhongguo aizheng zazhi
Subjects:
Online Access:http://www.china-oncology.com/fileup/1007-3639/PDF/20210415.pdf