The progress and prospect of homologous recombination deficiency detection in clinical diagnosis and treatment of cancer
Homologous recombination (HR) is the main way to repair DNA double-stranded breaks, single-stranded DNA gaps and stagnation or folding replication forks, helping to maintain telomeres and ensure the correct segregation of chromosomes during meiosis. Homologous recombination repair (HRR) pathway is o...
Main Author: | YU Li , SHEN Minna , JIANG Huiqin , WANG Beili , GUO Wei |
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Format: | Article |
Language: | English |
Published: |
Editorial Office of China Oncology
2021-04-01
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Series: | Zhongguo aizheng zazhi |
Subjects: | |
Online Access: | http://www.china-oncology.com/fileup/1007-3639/PDF/20210415.pdf |
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