Limited anti-inflammatory role for interleukin-1 receptor like 1 (ST2) in the host response to murine postinfluenza pneumococcal pneumonia.

Limited anti-inflammatory role for interleukin-1 receptor like 1 (ST2) in the host response to murine postinfluenza pneumococcal pneumonia.

Interleukin-1 receptor like 1 (ST2) is a negative regulator of Toll-like receptor (TLR) signaling. TLRs are important for host defense during respiratory tract infections by both influenza and Streptococcus (S.) pneumoniae. Enhanced susceptibility to pneumococcal pneumonia is an important complicati...

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Bibliographic Details
Main Authors: Dana C Blok, Koenraad F van der Sluijs, Sandrine Florquin, Onno J de Boer, Cornelis van 't Veer, Alex F de Vos, Tom van der Poll
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3590127?pdf=render

Internet

http://europepmc.org/articles/PMC3590127?pdf=render

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