Smallpox vaccination induces a substantial increase in commensal skin bacteria that promote pathology and influence the host response.

Smallpox vaccination induces a substantial increase in commensal skin bacteria that promote pathology and influence the host response.

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Interactions between pathogens, host microbiota and the immune system influence many physiological and pathological processes. In the 20th century, widespread dermal vaccination with vaccinia virus (VACV) led to the eradication of smallpox but how VACV interacts with the microbiota and whether this...

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Bibliographic Details
Main Authors: Evgeniya V Shmeleva, Mercedes Gomez de Agüero, Josef Wagner, Anton J Enright, Andrew J Macpherson, Brian J Ferguson, Geoffrey L Smith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-04-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009854

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https://doi.org/10.1371/journal.ppat.1009854

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