Vaccine-elicited IL-1R signaling results in Th17 TRM-mediated immunity

Vaccine-elicited IL-1R signaling results in Th17 TRM-mediated immunity

Abstract Lung tissue resident memory (TRM) cells are thought to play crucial roles in lung host defense. We have recently shown that immunization with the adjuvant LTA1 (derived from the A1 domain of E. coli heat labile toxin) admixed with OmpX from K. pneumoniae can elicit antigen specific lung Th1...

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Bibliographic Details
Main Authors: Joseph P. Hoffmann, Akhilesh Srivastava, Haoran Yang, Naoki Iwanaga, T. Parks Remcho, Jenny L. Hewes, Rayshma Sharoff, Kejing Song, Elizabeth B. Norton, Jay K. Kolls, Janet E. McCombs
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-06138-0

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https://doi.org/10.1038/s42003-024-06138-0

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